Severe generalized muscular atrophia, nerve optic atrophia, ear problem and disability with Pelger-Huet anomaly
Severe generalized muscular atrophia, nerve optic atrophia, ear problem and disability with Pelger-Huet anomaly
نویسندگان: نعیمه حمزه زاده نخجوانی , حسن محمودی
نشریه: Caspian Journal of Internal Medicine
, 2-2 , 245 - 248 ,
کد مقاله |
1259 |
عنوان فارسی مقاله |
Severe generalized muscular atrophia, nerve optic atrophia, ear problem and disability with Pelger-Huet anomaly
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عنوان لاتین مقاله |
Severe generalized muscular atrophia, nerve optic atrophia, ear problem and disability with Pelger-Huet anomaly
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نوع مقاله |
گزارش مورد |
IF |
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عنوان نشریه |
Caspian Journal of Internal Medicine
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شماره مجله |
2-2 |
دوره مجله |
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صفحه شروع و پایان |
- 248 |
نمایه نامه |
Chemical Abstract |
سال انتشار شمسی |
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سال انتشار میلادی |
2011 |
DOI |
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آدرس لینک مقاله/ همایش در شبکه اینترنت |
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Background: The Pelger-Huet anomaly dominantly is a rare and benign inherited defect of terminal neutrophil differentiation. Although neutrophil migration may be minimally impaired, granulocytes function is otherwise normal association abnormalities such as ocular, musculoskeletal are reported very rare.
Case: An eight year-old boy with good consciousness but severe muscular atrophia and difficulty in respiration was admitted in Amirkola Hospital at Babol University of Medical Sciences Babol, Iran. The patient was febrile at presentation. The chest x-ray was normal and other causes of respiratory problem were ruled out. The patient and his mother have 30% to 40% band and Pelger-Huet cells in peripheral blood smear. He gradually has gotten hearing loss and decreased visual acuity for three years. He has optic nerve atrophia.
Conclusion: The patient is an unusual type of Pelger-Huet anomaly with multiple organ dysfunctions probably due to simultaneous muscular degenerative disease |
نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |