Effects of Soy on Metabolic Biomarkers of Cardiovascular Disease in Elderly Women with the Metabolic Syndrome

Effects of Soy on Metabolic Biomarkers of Cardiovascular Disease in Elderly Women with the Metabolic Syndrome


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علوم پزشکی بابل
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نویسندگان: افسانه بختیاری , فرزاد جلالی

نشریه: Journal of Family and Reproductive Health , 4-3 , 95 - 104 ,

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کد مقاله 1234
عنوان فارسی مقاله Effects of Soy on Metabolic Biomarkers of Cardiovascular Disease in Elderly Women with the Metabolic Syndrome
عنوان لاتین مقاله Effects of Soy on Metabolic Biomarkers of Cardiovascular Disease in Elderly Women with the Metabolic Syndrome
نوع مقاله تحقیقی
IF
عنوان نشریه Journal of Family and Reproductive Health
شماره مجله 4-3
دوره مجله
صفحه شروع و پایان - 104
نمایه نامه سایر
سال انتشار شمسی
سال انتشار میلادی 2010
DOI
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Objective: To ascertain the effects of soy [in the forms of Textured Soy Protein (TSP) and soy-nut] on lipid profiles, apolipoproteins, inflammatory and prothrombotic markers and blood pressure in elderly women with the metabolic syndrome. Materials and methods: The study is a 12-week parallel randomized controlled trial that was conducted in rural health centres of Babol, Iran. The participants were 75 women 60-70 years old with the metabolic syndrome who were randomized to one of the three groups of soy-nut (35g/d), TSP (35g/d) and control. Blood pressure and blood biochemical markers were measured at baseline and at the end of the study including, triglyceride, cholesterol, HDL-C, LDL-C, VLDL-C, ApoB100, ApoAI, CRP and fibrinogen. Results: The soy-nut improved significantly LDL-C, VLDL-C and Apo B100 (P<0.05) while fewer improvements but significant were observed in these variables in the TSP group only when compared with the mean changes from the baseline (P<0.001). Similar result was found for Apo AI in the treatment groups (P<0.01). Serum total cholesterol decreased significantly in the treatment groups compared with control group (P<0.005). The differences from control for triglyceride, HDL-C, fibrinogen, CRP and blood pressure were not significant. Conclusion: Both forms of soy while improved lipids profiles the soy-nut contribution was more to this improvement than the TSP. Therefore, moderate daily intake of soy may be a safe, cheap and practical method to improve cardiovascular disease risk and also reduce the need for medical treatment.

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نویسنده نفر چندم مقاله
افسانه بختیاریاول
فرزاد جلالیششم

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