Active-passive Immunization Effectiveness Against Hepatitis B Virus in Children Born to HBsAg Positive Mothers in Amol, North of Iran

Active-passive Immunization Effectiveness Against Hepatitis B Virus in Children Born to HBsAg Positive Mothers in Amol, North of Iran


چاپ صفحه
پژوهان
صفحه نخست سامانه
چکیده مقاله
چکیده مقاله
نویسندگان
نویسندگان
دانلود مقاله
دانلود مقاله
علوم پزشکی بابل
علوم پزشکی بابل

نویسندگان: یوسف یحیی پور

نشریه: Oman Medical Journal , 26-6 , 399 - 403 ,

اطلاعات کلی مقاله
hide/show

کد مقاله 1277
عنوان فارسی مقاله Active-passive Immunization Effectiveness Against Hepatitis B Virus in Children Born to HBsAg Positive Mothers in Amol, North of Iran
عنوان لاتین مقاله Active-passive Immunization Effectiveness Against Hepatitis B Virus in Children Born to HBsAg Positive Mothers in Amol, North of Iran
نوع مقاله تحقیقی
IF
عنوان نشریه Oman Medical Journal
شماره مجله 26-6
دوره مجله
صفحه شروع و پایان - 403
نمایه نامه Pubmed
سال انتشار شمسی
سال انتشار میلادی 2011
DOI
آدرس لینک مقاله/ همایش در شبکه اینترنت

چکیده مقاله
hide/show

OBJECTIVES: HBV infection is a contagious disease that may transmit vertically from mothers to their neonates or horizontally by blood products and body secretions. Over 50% of Iranian carriers have contracted the infection perinatally, making this the most likely route of transmission of HBV in Iran. This study assesses the serologic markers of HBV in children born to HBsAg positive mothers who received HBIG and 3 doses of HBV vaccine. METHODS: To evaluate the effectiveness of vaccination against HBV, a study was conducted on 95 Children, born to hepatitis B surface antigen (HBsAg)-positive mothers, who had received Hepatitis B Immune Globulin and HBV vaccines during 2004-2008. All children were tested for the presence of HBsAg, anti-HBs and anti-HB core antigen (anti-HBc). RESULTS: Among an estimated 30000 pregnant women during the five year study, about 130 (0.42%) were HBV carriers. Ninety-five children from these mothers were enrolled in this study. Only one child (1.1%) was HBsAg positive, while 88.4% of children were Anti-HBs Positive. Eleven children (11.6%) were exposed to HBV as shown by the presence of anti-HBc. A significant difference was observed between the children's age and Anti-HBs (p=0.0001). CONCLUSION: Passive-active immunoprophylaxis of high risk babies was highly efficacious in preventing perinatal transmission of the HBV carrier state. Also, evaluation of serologic markers in HBV infected people is important for designing the strategies for disease control.

نویسندگان
hide/show

نویسنده نفر چندم مقاله
یوسف یحیی پوراول

دانلود مقاله
hide/show

نام فایل تاریخ درج فایل اندازه فایل دانلود